Law-ref.org REACH - Registration, Evaluation and Authorisation of Chemicals
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ARTICLE-44: Criteria for substance evaluation     [go to this ARTICLE]
... (a) hazard information, for instance structural similarity of the substance with known substances of concern or with substances which are persistent and liable to bio-accumulate, suggesting that the substance or one or more of its transformation products has properties of concern or is persistent and liable to bio-accumulate; ...